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Although this in vitro setup enables us to get a global overview of the adipogenic response during critical illness, it cannot distinguish between specific effects of individual factors present in the serum of critically ill patients.
By using siRNA resistant flotillin-1 or -2 we were able to distinguish between specific effects of flotillin-1 or flotillin-2.
Thus, the analysis of the control RNAi experiment can be very important in order to distinguish between specific effects arising from the RNAi, and background effects due to the baseline behavior of the cell line.
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FE model introduces the olive oil specific effect, providing consistent estimates regardless of correlation between the specific effects and the independent variables.
Recent studies have also described the relationship between the specific effects of pediatric chronic disease in children and HRQOL.
However, although dietary interventions have been associated with several disturbances in rodents, a clear distinction between the specific effects of each dietary macronutrient in relation to metabolic and cardiovascular disturbances has not been clarified in literature.
A distinction should be made between nonspecific and specific effects.
In the light of the apparent conflict between lack of specific effects from verum acupuncture and large subjectively experienced positive effects it seems interesting to evaluate if acupuncture has antiemetic effects related to nonspecific mechanisms.
In addition to our in vivo measure of virulence, we also measured growth on solid medium so that we could distinguish between QTL with specific effects on virulence from QTL affecting growth both in vitro and in vivo.
Logistic recalibration showed no significant differences between the overall hospital specific effects of the predictors compared with the overall effects of the predictors in the clinical model (fig 2).
However, we cannot distinguish between a specific effect of ARNTL on p21CIP1and a more general effect of ARNTL on p53 transcriptional activity.
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