Sentence examples for between somatic mutations and from inspiring English sources
Correlations between somatic mutations and first-line targeted therapy outcomes have not been reported on a randomized trial.
All verified changes were resequenced in parallel with the matched normal DNA, to distinguish between somatic mutations and SNPs not previously described.
All confirmed changes were resequenced in parallel with the matched normal DNA to distinguish between somatic mutations and SNPs not previously described.
All verified changes were re-sequenced in parallel with the matched normal DNA from blood samples to distinguish between somatic mutations and SNPs not previously described.
All verified changes were resequenced in parallel with matched normal DNA to distinguish between somatic mutations and SNPs not previously described.
It is likely that non-genetic and genetic alterations interact during tumourigenesis and several studies have identified interactions between somatic mutations and micro-environmental changes (Garcia et al. 2014), inflammation (Kwon et al. 2014) and metabolism (Kalaany & Sabatini 2009).
To determine the relation between somatic mutation and gain of gene copy number of PIK3CA gene in breast cancer, we integrated our mutation and gene copy number data.
Because microsatellite data only provide information on fragment length, and null alleles are often present, it was impossible to distinguish between somatic mutation and scoring error.
We did not observe a significant association between somatic mutation and gain of PIK3CA gene copy number in 92 cases of breast tumors (Table 2).
Atomic bomb survivors are a population suitable for studying the relationship between somatic mutation and cancer risk because their exposure doses are relatively well known and their dose responses in terms of cancer risk have also been thoroughly studied.
Using partial correlation analysis [ 22], we obtained a compact and highly specific GBM network of causative relations between somatic mutations, methylation, and transcription (22,990 links between 15,197 gene symbols; (manuscript in preparation).
