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Studies of persons with naturally acquired malaria immunity have shown an inconsistent relationship between serologic and functional antibody responses [17], [27].
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Blood stage antigen (AMA-1 and MSP-1) vaccine studies in malaria experienced individuals demonstrate variable serologic and functional antibody responses, depending on the antigen tested [13], [28], [29].
Detailed demographic, clinical, echocardiographic, serologic and functional testing data were also collected.
We excluded studies reporting only serologic findings because of potential cross-reactivity among related viruses and poor correlation between serologic status and concurrent infection.
Choose between chronological and functional resume formats.
Finally, we evaluated whether the serologic, capillaroscopic, clinical and functional parameters were predictive of the development of additional clinical and/or functional alterations in patients with early SSc.
Considering the relationships between serologic response and BMPC percentage, patients were reclassified as four groups (<5% BMPCs + serologic CR versus <5% BMPCs + serologic non-CR versus ≥5% BMPCs + serologic CR versus ≥5% BMPCs + serologic non-CR) and entered into the multivariate models.
No association was found between serologic status and hepatomegaly or splenomegaly.
Figure 3 shows the relation between serologic CR and BMPCs before PBSC mobilization.
Finally, we observed significant associations between serologic status and disease outcome of CIN3/cancer diagnosed during follow-up as shown in Table 4 > -wrap-foot>.
Ordinal logistic regression analysis was used to investigate whether there was an association between serologic results and the degree of liver fibrosis, stratified by ecosystem.
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