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We further evaluated the relationship between sequence depth and rate of known events and racall values.
Regions of CN loss were also identified, but we observed a positive correlation between sequence depth and regions of CN loss.
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The relationship between sequencing depth and efficacy in the comprehensive detection of SNPs is a key concern from the perspective of cost-effectiveness.
The relation between sequencing depth and the number of high quality genotypes.
The correlation between sequencing depth and template abundance is insufficient to precisely arrange mutations within these groups.
This is particularly relevant when many related samples are being sequenced and one needs to assess the trade-offs between sequencing depth and sample coverage.
To determine the relationship between sequencing depth and AS detection power, the sequencing library (Ye478) was first used to randomly create sub-libraries to detect AS transcripts.
This approach, although appropriate based on available data regarding the relationship between sequencing depth and mutation clonality, discards a wealth of information.
For functional analysis, the trade-off between sequencing depth and the number of biological replicates for each condition must be carefully balanced [ 37].
We also note that INPUT-seq with higher sequencing depth (>4 million mapped reads) tend to cluster together more tightly than those with lower sequencing depth, suggesting that there may be a relationship between sequencing depth and input DNA variability.
Interestingly, the scaffolds built here appear to maintain some correlation between sequencing depth and low complexity repeats (SSRs) sampling, whereas other categories of identifiable repeats are obtained already at lower sequencing depth (see Canopy_Next in fig. 4 A).
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