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To investigate the relationship between sequence conservation and thermodynamic stability, we compared the thermodynamic stability of conserved and non-conserved pre-miRNAs from human, mouse, and chicken genomes, with special emphasis on ultra stable and unstable pre-miRNA sequences.
These results now allow us to examine the relationship between sequence conservation and the folding process, particularly viewed through the analysis of transition state (TS) structure.
In order to see how drug therapies can influence the relationship between sequence conservation and CD4+ T-cell levels, we performed the same study on the data of untreated patients included in the therapy-naïve dataset.
We investigated the relationship between sequence conservation and function of TF genes in C. elegans.
A correlation was identified between sequence conservation and thermodynamic stability for pre-miRNAs from human, mouse, and chicken genomes.
A correlation between sequence conservation and protein function/tissue-distribution/expression has been the focus of several studies [ 40- 44].
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Relationships between sequence conservation statistics and HI were examined through the Mann-Whitney U-test, calculation of z-scores, and drawing of ROC curves as described for S. cerevisiae.
We found a positive correlation between miRNA sequence conservation and expression level.
To distinguish between genome sequence conservation and transcription factor binding site conservation, we will use the word "retention" to describe binding sites that are present in both species in the corresponding genomic region.
Secondly, changes in promoter sequence could potentially cause changes in gene expression, so we extended the evaluation of promoters to examine the relationship between upstream sequence conservation and local network similarity.
In addition, however, a correlation between sequence conservation in the exon ends and intron length, particularly, in synonymous positions, was observed throughout the entire length range of introns.
More suggestions(15)
between sequence structure and
between energy conservation and
between habitat conservation and
between sequence evolution and
between sequence depth and
between miRNA conservation and
between wildlife conservation and
between promoter conservation and
between power conservation and
between site conservation and
between sequence variability and
between microRNA conservation and
between sequence divergence and
between sequence identity and
between sequence variation and
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