Sentence examples for between sequence and methylation from inspiring English sources
Of significant biological interest is the conclusion from the adjusted analysis that the mode of regeneration has no significant effect on the balance between sequence and methylation state change induced by the tissue culture process.
Of significant biological interest is the conclusion that the mode of regeneration has no significant effect on the balance between sequence and methylation state change induced by the tissue culture process.
In addition, we found a positive correlation between sequence length and methylation density for genes, but not for TEs, which is different from the case in A. thaliana wherein both genes and TEs showed positive correlation between sequence length and methylation [ 12].
Parallel profiling of the methylation status of this catalogue of sequences allowed us to derive a comprehensive dataset that permits the systematic association between sequence motifs and methylation states.
We also found striking correspondences between genome sequence and histone methylation in ES cells, which become notably weaker in differentiated cells.
The link reported between DNA sequence and DNA methylation offers a possible functional role to seemingly non-functional SNP associations.
Having derived this observation from a large pool of sequences opens the possibility to infer quantitative relationships between sequence composition and resulting methylation.
The relationship between sequence variants and DNA methylation patterns in different sets of individuals may also provide insight into complex traits in which a particular environmental exposure associates with a trait only if incurred at a particular developmental window.
The methylation status of the galanin promoter was studied using bisulfate sequencing and methylation-specific PCR.
We initially showed using bisulphite sequencing and methylation-specific PCR that RasL12 is subject to CpG island methylation in many breast carcinoma cell lines, with a perfect correlation between bisulphite sequencing and methylation-specific PCR and downregulated expression of RasL12.
