In clinical lymphomas, methylation of Leprel2 and P4HA2 was a sensitive and specific discriminator between BL and DLBCL.
ROC analysis was plotted to determine the best cut off range for healthy individuals compared with cancer group screening EDIM-Apo10 and EDIM-TKTL1 expression to allow a sensitive and specific discrimination between cancer patients and healthy individuals.
The lncRNA expression levels allowed highly sensitive and specific discrimination between RCC and control subjects as determined by using ROC analyses: the area under the curve was >0.9 for all dysregulated samples, especially lnc-CPN2-1 overexpression allowed molecular identification of RCC tissue (AUC 0.942, 95% confidence interval 0.884 1.000).
Tests for latex-specific IgE such as the RAST are less sensitive and specific than are skin prick tests, with sensitivity ranging between 73 and 80% and specificity ranging between 90 and 97% (Ownby 2003).
Expression of PRDX2 and TPM4 in the cytoplasm was associated with both the highest sensitivity and specificity for differentiation between SCE and InvSCC, and expression of PRDX2 and ANXA6 in the cytoplasm was the most sensitive and specific for differentiation between MicSCC and InvSCC.
Nonetheless, we have demonstrated that CARS imaging is reliable, sensitive and specific in discriminating between different subtypes of breast cancer, e.g., non-invasive in situ vs. invasive, different histological subtypes, e.g., DCIS vs. IG-IDC & ILC, and different histological grades of carcinoma, e.g., intermediate vs. high grade.
We conducted simulations for three time-points t and with three relationships between the predictor and event: the predictor equally sensitive and specific, the predictor more specific, and the predictor more sensitive.
According to Shumway-Cook et al, [ 31] the TGUG is a sensitive and specific measure for discriminating between fallers and non-fallers in community-dwelling adults.
The importance of the interaction between HIV and TB urges us to develop a highly sensitive and specific test for the detection of LTBI amongst HIV positive patients.
A highly sensitive and specific T7 phage library discriminates the immune signature between sarcoidosis patients and TB.
