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A nested case-control study was conducted to examine the associations between selective polymorphisms of ESR 1, ESR2 genes and the risk of developing prostate cancer in a community-based cohort in Washington County, Maryland.
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Yang, S.-J. et al. Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis.
There was a significant association between combined polymorphisms of 5-HT1A and BDNF polymorphisms.
However, the relation between polymorphisms of HDC gene and CHF risk remains unclear.
Thus, the variation patterns across species point to currently unrecognized polymorphisms of selective (and hence functional) importance in ABO.
The value of the scaled fitness difference between selective classes which best fits the observed skew for regulatory polymorphisms is 2.1 (95% CI based on the binomial distribution approximately 1.6 2.7).
This software was also used to assess linkage disequilibrium (LD) between polymorphic sites, and selective neutrality of observed polymorphisms (D, D* and F*, D* and F* with outgroup, [28], [29]).
The trend is even apparent for schools in highly affluent areas of Sydney and Melbourne, though these have the smallest gap between selective and non-selective.
No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease.
Association between polymorphism of the insulin receptor gene and migraine provided inconclusive results.
R. C. Lewontin and J. Krakauer, "Distribution of Gene Frequency as a Test of the Theory of the Selective Neutrality of Polymorphisms," Genetics 74 (1973) 175-195.
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