Because substitution rates are determined, to a great extent, by the balance between selection and genetic drift [ 8], we studied the changes in selective pressure in frogs, and found that purifying selection acting on most mt and some nuclear proteins might have been relaxed in Neobatrachia.
In coastal lakes, PST ≈ FST for these estimates making distinctions between selection and genetic drift equivocal.
We therefore suggest that an interaction between selection and genetic drift explains the patterns of divergence in throat color morphs.
These results suggest that there is an interaction between selection and genetic drift causing divergence even at a phenotypic level in these small, subdivided populations.
The interplay between selection and genetic instability in shaping tumor genomes is currently most clearly established in tumors with defects in mismatch repair.
The fixation probability of a mutant is useful for predicting short-term evolution and to understanding how the interplay between selection and genetic drift affects the fate of a new mutation.
