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Discrepancies exist between scores obtained using the self-completed and practitioner-administered versions of the MNA-SF in group 3 as five patients (12%) were misclassified.
For many individuals, there was also a mismatch between scores obtained using the PGI and those obtained with the EQ-5D (i.e. individuals with scores as low as 0.1 on the PGI had scores of 0.8 on the EQ-5D).
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In test cases with millions of potential paths, the correlation between the node scores obtained using the exact objective and those obtained with the approximated objective when only using was >0.999 (Supplementary Figs S1 and S2).
To determine the preferred methodology for the analysis of our microarray data we compared the correlation between microarray expression scores obtained using two different data normalization procedures – Affymetrix MAS 5.0 [ 8], and robust multi-array analysis (RMA)[ 9] – with the expression levels obtained from follow-up verification experiments using qRT-PCR [ 10- 12].
This method was chosen after it had been ascertained that no statistically significant differences occurred between the overall mean scores calculated in this way and the overall mean scores obtained using only complete questionnaires.
Z scores obtained using EpiInfo 3.5.1 Nutrition program.
The Pearson correlation coefficient between the chewing function score obtained using the alternate version of the questionnaire and the OHIP-14 summary score was r = -0.46 (N = 490, 95% CI: -0.53 to -0.39), indicating that subjects with higher chewing function scores (which reflect better self-reported chewing ability) had lower OHIP scores (which reflect less impaired OHRQoL).
There was agreement between the manager's opinion and the score obtained using the questionnaire.
Bias 2: mean score after imputation – mean score obtained using standard scoring rules.
The total score obtained using this scale was called the single dyspepsia symptom (SDS) score.
Postoperative functional scores were obtained using the mobility score of Parker and Palmer [ 39].
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