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The genes up-regulated in protoplasts were identified using the following criteria for differential expression: a FDR level less than 0.05 and expression level difference between samples of at least four fold.

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Our results show that currently available technologies, while allowing comparisons between samples of a given protein at a fixed concentration, may be unable to measure particle numbers accurately in a variety of protein formulations, e.g., at high concentration in sugar-based formulations.

To what extent, if any, an underlying neuropathology may contribute to this discrepancy between samples of human sural nerve taken at biopsy and isolated human DRG-somata is also not known.

Transcripts were found to be differentially expressed between samples of the same genotype collected at different times.

The proteins identified as up- or down-regulated in at least two of three independent experiments with a difference between PME-1 and samples of at least two fold were considered significant hits and were manually validated (Tables 1 and 2).

FT rheology was used to study the non-linear viscoelastic behavior and the results also show marked difference between samples collected at various stages of the process, the ratio I(3ω1)/I ω1) decreasing along the extruder.

Significance of differences between samples fixed at the 0.05 probability level for all statistical tests was checked with the Mann–Whitney U test.

We also performed PDS, which is a very sensitive optical absorption technique, to compare the density of states between samples annealed at different temperatures.

There were no significant differences between samples obtained at different stages of the cycle (P = 0.679), although there was a suggestion that the levels were higher in the proliferative and early secretory phases (Fig.  1A).

The intraclass correlation coefficients (ICCs) for the proportions of each metabolite between samples taken at different points in time ranged from 0.45 to 0.68 (Steinmaus et al. 2005).

For 2D- l 1-SVD- 1-SVD-re exists a coherence between the samples of sub-arrays at different columns of the array as far as the estimation of α is concerned, so 2D- l 1-SVD- α can process M/2 differentherend up to N/2 diffexistsβ for eacoherence

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