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"We've known for some time about the probable link between red and processed meat and bowel cancer, which is backed by substantial evidence.
To provide a quantitative assessment of the association between red and processed meat intake and the risk of esophageal squamous cell carcinoma (ESCC), we summarized the evidence from observational studies.
This week, the Internet was aflutter with commentary on the recently released World Health Organization (WHO) report affirming the connection between red and processed meat and cancer.
10 A 2008 expert review also adds breast, bladder, and oral cancer to the list. 2 This link between red and processed meat and cancer is supported by a recent prospective study addressing the relationship between meat intake and mortality.
In summary, we observed suggestive positive associations between red and processed meat, as well as grilled meat, well or very well-done meat, PhIP, haeme iron, and nitrate/nitrite and distal colorectal adenoma.
Thus, misclassification of red and processed meat consumption and of potential confounders might have resulted in an over- or underestimation of the association between red and processed meat consumption and risk of pancreatic cancer.
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This link between barbecued meat and kidney cancer comes after the World Health Organisation and International Agency for Research on Cancer reported that red and processed meats are carcinogenic.
"This decision doesn't mean you need to stop eating any red and processed meat.
More bad news for red and processed meat.
We found no statistically significant associations between the PXR and LXR polymorphisms and CRC risk, and no interaction with smoking status, use of NSAID, or intake of red and processed meat.
The found interactions between MDR1 polymorphisms and intake of meat in the present study suggest that the MDR1 polymorphisms may be of minor importance in study populations with a low intake of red and processed meat.
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