Elimination of telomeric and centromeric windows has no effect in chicken where the difference between sex-specific recombination pattern and GC* correlations remain small and nonsignificant (P value = 0.062).
The model accounts for the joint recombination pattern, the asymmetry between maternally and paternally derived X chromosomes, and the finiteness of population size.
A starting haplotype is then randomly chosen and the script imposes the recombination pattern on the marker positions and switches between haplotypes as needed to simulate recombination.
Differences in the recombination patterns between male and female meiosis may partly account for the striking gender- and chromosome-specific differences in the genesis of human aneuploidy, especially in aged oocytes.
The regional recombination pattern differences between sexes are illustrated in linkage maps presented in Additional file 2 (chromosomes.zip).
Moreover, by combining in silico and experimental approaches, we studied the recombination pattern of specific chromosomes that have suffered rearrangements between human and macaque lineages.
The complexity of the recombination patterns between vaccine and challenge viruses suggest that repeated events of super-infection with both viruses replicating concurrently must occur to allow for recombination to occur.
This is a more stringent test than the previous overall comparison between FST and recombination patterns, since, rather than general means, data points correspond now to 1000 windows a 1 Mb each.
Different possibilities account for the sex-specific differences: first, the differences in the recombination patterns between male and female meiosis; second, more permissive checkpoints in females than males; third, the age-related loss of chromosome cohesion in female gametes; and fourth, the difference in the ability to detect the consequences of meiotic division errors [5], [11] [15], [34].
Haplotypes contain more detailed information than genotypes and are valuable for GWAS [ 6], and for analyzing genetic structures such as linkage disequilibrium, recombination patterns [ 1], and correlations between variations and diseases [ 7].
