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There are many similarities between randomized controlled trials and meta analyses.
The discordance in coronary heart disease outcome between randomized controlled trials and observational studies is a function of the differences in study design and the characteristics of the populations studied.
For example, review criteria for statistics and methodology differ between randomized controlled trials and qualitative studies.
The non-interventional real life study design of DACCORD aims at bridging the gap between randomized controlled trials and clinical reality.
The T-test was used to compare minor and major inconsistencies, the CONSORT and STROBE score, and the impact factors between randomized, controlled trials and observational studies.
8 29 Our results corroborate those of a recent Cochrane review, which showed that drug effects were usually similar between randomized controlled trials and observational studies.
Similar(54)
Modelling studies represent an alternative to randomized controlled trials.
We restricted the search to randomized controlled trials.
13 Most randomized controlled trials reported between 7% and 53% of the 15 items; two adequately reported more than 60% of the items.
We systematically searched Medline, Web of science and Cochrane Library for prospective randomized controlled trials published between Jan 1 , 1996and July 1, 2015 that recorded cardiovascular outcome trials of glucose-lowering drugs or strategies in patients with type 2 diabetes mellitus.
All included randomized controlled trials reported about the length of stay, which varied between the 4.7 days and 42.7 days.
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