Sentence examples for between randomised controlled trials from inspiring English sources
Our analyses, however, have shown little or no heterogeneity between randomised controlled trials for all outcomes.
Recent reports have highlighted the distinct roles and occasional tension between randomised controlled trials (RCTs) and population-based observational research (Concato, 2012; Hershman and Wright, 2012; Goodwin et al, 2013).
Fourthly, durations of follow-up and treatment varied between randomised controlled trials, which could limit the interpretation of the meta-analysis for a specific length of treatment.
Despite its shortcomings, this careful, albeit not exhaustive, comparison between randomised controlled trials and observational studies using data from an electronic primary care medical record database reveals several important insights.
Discrepancies between randomised controlled trials and observational studies have been shown in a meta-analysis, 28 which reported for randomised trials a 90.3%95%CI89.8%to8% to 90.8%) adherence at 1-year follow-up against 49%95%5% CI 48.9%too 49.2%) for observational studies.
However, there was no significant difference in effects between overall randomised controlled trials and observational studies.
Therefore, the association between significant inconsistency and fewer randomised controlled trials may be partly due to the "small study effect".
To investigate whether there is a difference in the treatment effect of donepezil on cognition in Alzheimer disease between industry-funded and independent randomised controlled trials.
Third, there is often not a one-to-one relationship between studies and publications: most randomised controlled trials will report at multiple follow-up intervals; many will issue multiple publications at the same time point.
Twenty completed randomised controlled trials 5 8 14 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 enrolling 46 099 patients, lasting between 12 and 85 months, reported the effects of fibrates on the included outcomes (table 2).
