Sentence examples for between proliferative signalling pathways from inspiring English sources

E2Fs represent hence the link between proliferative signalling pathways, triggering clonal expansion and terminal adipocyte differentiation through regulation of PPARγ expression.

Src plays an important role in the cross-talk between proliferative signalling pathways downstream of receptors such as the ER, IGF1R and the EGFR family, and src kinase activity is enhanced in breast cancer patients, making it a potential target for targeted therapeutics.

Atherosclerosis is a complex, chronic disorder involving inflammatory and proliferative signaling pathways.

These products of post-translational c-Flip processing are known to promote ERK and NF-κB proliferative signaling pathways.

Acquired resistance develops through various mechanisms including secondary mutations of the targeted oncogene or activation of alternative proliferative signaling pathways.

Two such molecules are sunitinib and sorafenib, multi-kinase inhibitors, blocking PDGF, VEGF and other pro-proliferative signalling pathways.

However, NF-κB activity is not essential due to simultaneous proliferative signaling pathway activation.

Conversely, re-expression of ERβ in ER negative cells confers a more epithelioid phenotype, decreases their capacity for anchorage independent growth and down-modulates proliferative signal transduction pathways.

EGFR activates proliferative and antiapoptotic signalling pathways, such as the phosphatidylinositol 3' kinase/Akt and Ras/Raf/mitogen-activated protein kinase (MAPK) pathways [6].

These results indicate that external stimuli, that normally induce proliferative or survival signalling pathways, cannot negate the apoptotic effect of TSA on CD4+ T-cells.

Cell cycle is a conserved proliferative signaling cascade pathway in mammals and comprises the G1, S, G2, and M phases.