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In addition, genetic differences were further analysed using a correspondence analysis (CA) of the allele frequencies to detect differences and similarities between populations, using the BiodiversityR48 package in R software.
To scan for evidence of differences in recent selection between all of the sampled endemic sites in the region, the relative breakdown in haplotype homozygosity with distance from each SNP was compared between populations using the Rsb metric (which contrasts data for each pair of populations sampled).
Quantitative assessment of similarities between populations (using the Morisita-Horn similarity index) indicated that the nares, axilla and groin harbor distinct and temporally stable microbial communities (Figs. 2 and 3, Table 2).
In this method, genome-wide SNP data is used to analyze differences in the haplotype frequency, nucleotide diversity, and LD between populations, using the ratio of haplotype homozygosity between populations.
When possible, we performed pairwise comparisons of LD patterns between populations using the Spearman rank correlation value, and found that they are quite different in most cases (Table S9).
DNA sequence variation was measured within and between populations using the McDonald-Kreitman test [ 52].
Similar(45)
Although we recognize that cultural differences exist between populations using these languages that might increase the heterogeneity of responses between participants, this should not affect our ability to reach our primary objectives of determining feasibility, and variance estimates for sample size calculations of a definitive study.
Specifically, multiple forms of reproductive isolation, such as habitat and sexual isolation, are stronger between pairs of populations using different hosts than between pairs of populations using the same host [33], [75], a signature of the process of ecological speciation [15] [19].
There were few differences between the patient populations using the two different monitors.
We compared survival probabilities between the two populations using the 'ESTIMATE' statement in NLMIXED.
As second analysis, we computed a matrix including pairwise FST values between all sampled populations using the estimator θ of the parameter FST (Weir and Cockerham 1984).
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