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There were no statistically significant (p>0.36, Mann-Whitney U test) differences in PCS or MCS scores at index between patients completing the questionnaires and non-completers, nor at any of the follow-up periods.
There also were no significant differences between study centers, or between patients completing the full study and drop-outs at different time points, with the exception of higher baseline insulin dose in drop-outs vs. completers (not shown).
There were no statistically significant differences in Whiteley-7 scores at index consultation between patients completing the questionnaires and patients declining to complete at any follow-up times (Mann-Whitney U test, p>0.086 or higher) (details available from the authors on request).
Any difference between patients completing the intervention and those not completing (dropouts) will be carefully discussed when evaluating the intervention, results and the suitability for implementation.
Of note, there were no statistically significant differences in demographic and study characteristics between enrolled subjects and those not enrolled, or between patients completing the study and those lost to follow-up.
There was no difference in the preoperative values of total power, LF, HF or the LF/HF ratio for all 3 body positions between patients completing the 6 h mobilization test and those terminating the test prematurely due to OI (Table 3).
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Although we hypothesized that impaired postoperative autonomic blood pressure regulation is a general defect related to surgery or anaesthesia, the reduced sample size at 6 h precluded analysis of whether orthostatic HRV responses could predict the occurrence of postoperative OI or whether HRV responses differed between OI patients and patients completing the mobilization procedure.
Moreover, there were no significant differences in gender, age, and cancer diagnosis between the dropouts and those patients completing the study.
Between January 2011 and January 2012, 2546 patients completed the questionnaire (Table 1).
Sheets explaining the study procedure with consent to be called were left in examination rooms by clerks upon setting up between patients, completed by parents while the child waited to be seen, and picked up by clerks upon patient's discharge.
Between January 2008 and October 2008, 100 patients completed the 60-day study period: 50 patients from each group.
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