Sentence examples for between pathway activation and from inspiring English sources

No significant association was found for medulloblastomas in this study between pathway activation and survival.

The link between pathway activation and a better prognosis has also been identified in medulloblastoma (Ellison et al, 2005; Gajjar et al, 2006; Ellison et al, 2010), where pathway status is now being planned to be used for disease risk stratification in forthcoming medulloblastoma clinical trials (Pizer and Clifford, 2009; Ellison et al, 2011).

This study is the first to extensively investigate the status of the WNT/ β-catenin pathway in CNS PNETs and has shown pathway activation in a high proportion of tumours (36%), as well as suggested a link between pathway activation and a more favourable outcome.

Another striking linkage between Hh pathway activation and MMTV-Wnt1 expression was found in melanocytic hyperplasia under the nipple region (Fig. 6E box).

While up-regulation of IMD pathway components in response to DENV infection was not observed in the cell line or in the mosquito [5], this lack of regulation may be attributable to a balance between IMD pathway activation and DENV suppression of this pathway.

Recently, several works have demonstrated a connection between Notch pathway activation and the regulation of cell motility and invasiveness.

One of such pathways, where a clear correlation between abnormal pathway activation and disease progression has been observed, is the Sonic Hedgehog (Shh) signaling pathway [1].

Data from primary breast tumors suggest a causal relationship between PI3K/Akt/mTOR pathway activation and overexpression of HER2, implicating the pathway in progression of HER2-positive breast cancer [ 21].

As secondary, exploratory end points, we evaluated the associations between PI3K pathway activation and time to distant recurrence (TTDR) and time to BCBM.

Because of the variability in epigenetic pathway activation within certain cancers, we examined the relationship between epigenetic pathway activation and known subtypes of two common cancers with well-defined subtypes: breast cancer and glioblastoma.

DUSPs are key regulators of the balance between kinase pathway activation and inactivation, and have previously been reported to be upregulated in an adaptive response, creating a negative feedback loop following MAPK pathway activation (Keyse, 2008).