Among primate lentiviruses, a correlation is observed between viral pathogenicity and expression of Vpu, with CD4+ T cell decline and progression to AIDS markedly faster in HIV-1 than HIV-2, and increased mortality in chimpanzees infected with SIVcpz (Keele et al., 2009).
We evaluated several potential mechanisms that could underlie the positive association between pathogenicity and attractiveness of prey bacteria.
Host-specific parasites reach the optimal level of pathogenicity by maintaining the trade-off between pathogenicity and transmissibility.
The association between pathogenicity and fractions of YR stretches is assumed to be linked to recombination and horizontal transfer.
tabacum interactions, and to assess whether A. tumefaciens has a direct or plant-mediated effect on pathogen growth, behaviour and expression of pathogenicity factors.
Major differences between pathogenicity islands and mobile elements are also likely driving the evolution of V. parahaemolyticus.
Further investigations are needed to clarify any possible link between the pathogenicity and genetic diversity of SAFV.
Transfer of the PAI and expression of pathogenicity-associated factors encoded within it prompted us to compare the pathogenicity of the E. faecalis isogenic strains carrying and lacking the PAI.
Therefore, a simplification of the relationship between ecological niche, pathogenicity and phylotype is not possible, and these findings forced rickettsiologists to define more carefully rickettsiae as either pathogenic or of unknown pathogenicity.
Furthermore, the two-component systems PhoQ/PhoP and AstS/AstR have been shown to be involved in the regulation of mutualism and/or pathogenicity gene expression [ 27, 28], and are believed to be members of a putative complex regulation network that coordinates the switch between mutualism and pathogenicity [ 2].
