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For most clones, modified eBURST analysis does not detect meaningful relationships between other cell types.
The four WAT sites analyzed constitute a large proportion of the total rat's large anatomically distinguishable WAT [ 3], and its function may be somewhat different from the ancillary role of adipocytes interspersed between other cell types in a number of organs or tissues, such as muscle [ 5].
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The separate analyses of the correlation between the other cell types present in the tumor epithelium or the tumor stroma compartment and survival were not significant.
In addition, interactions between tumor and other cell types give rise to a complex supra-cellular communication network.
In EPs/ECs and EPs/FBs, IL-6 and IL-8 were significantly increased compared to monocultures (Figure 7A), suggesting interactions between EPs and other cell types activate an inflammatory response in vitro resulting in EP remodeling that may play a role in EP bridge formation.
Examples of non-cell autonomous signalling extend to interactions between keratinocytes and other cell types.
One main difference between hepatocytes and other cell types is that hepatocytes do not express Alox5.
Neuropeptides are important mediators in the nervous system and between neurons and other cell types.
These could include modulating cell-cell interactions or signalling between cancer and/or other cell types.
The interactions between hepatocytes and other cell types have significant consequences in the initiation and progression of hepatotoxicity in vivo.
AIF-1 may play a paracrine role in the regulation of WAT function through cross-talk between macrophages and other cell types within the adipose tissue.
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