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Specifically, the LOC and parahippocampal areas were significantly more active when objects were presented in normal context while frontal and parietal areas became engaged when the relationship between object and context was unexpected.
Conversely, the altered balance between object and context processing predicted by our model is a novel notion, which has not yet been tested directly (although there are some interesting studies suggesting that object and spatial processing are differentially affected by schizophrenia in other cognitive domains, including visual perception[75], mental imagery[76] and working memory[75]).
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The linkages between objects and context could form a neuronal basis of episodic memory[38] [41].
The distinction between object- and context-focus in Westerners and East Asians has been conceptualized as generally greater attention to specific elements within a given picture.
"Slowing things down to an extreme measure creates room for appreciation of the object… but the prolonged duration also starts to shift the relationship between object, viewer, and context.
However, in the schizophrenic model, the reduced connectivity between input layers and entorhinal module leads to incomplete convergence of object and context input onto the entorhinal module (Figure 2b).
Object and context representations consisted of eight nodes each, activated in the object and context layer, respectively.
When both object and context cues are available, (e.g., in recognition, source monitoring or lexical disambiguation) object cues will tend to override context cues.
How object and context information are processed and represented can thus be observed directly.
Entorhinal feedback connections to the object and context modules produce the model output.
Together, these data suggest that the LEC is critical for recognition of all the possible associations between objects, places and contexts and is not required for nonassociative, independent recognition of any of these components (objects, places, or contexts).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com