Mixing of nuclei of different colors reflects noise.
The most obvious difference between nuclei from different fixation procedures is a distortion of nuclear shape by some methods.
In contrast to our findings in BSE infected red deer where prominent intra-neuronal labelling of PrPd was found, intra-neuronal deposits are reportedly rare in CWD affected animals and when present are mild and scattered within and between neurones of different nuclei; mainly in the brainstem [ 29] and the cerebellar deep nuclei [ 30].
By contrasting data from Parkinson's disease patients recorded both OFF and ON dopaminergic medication, we are able to associate different levels of optimal phase alignment between these nuclei with different levels of functional performance of the basal ganglia, as inferred from changing levels of motor impairment with medication.
(2) How do dsRBDs discriminate between dsRNA of different sequences, abundant in the cell nuclei and cytoplasm?
Hyphal fusion between strains of different species, followed by nuclear fusion leading to the creation of a stable, diploid nucleus, seems more plausible.
However we agree we have overstated the case regarding the fate of the nucleus by not discussing the alternative interpretation of independent occurrence of nuclei in different cell lines (the question of homology between the eukaryotic nucleus and that of Gemmata).
This means that the dose distribution within the cell nucleus at microscopic levels is very important for comparison of the real differences between the radiotoxic effectiveness of different radionuclides.
In spite of their small size, nuclei have been studied experimentally for many decades, and this work has enabled the measurement and classification of energy states in a very large number of different nuclei.
Therefore, the nucleation and growth processes could only complete by colliding of different nuclei around themselves.
