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Exact(2)
Since LARS2 does not influence either the thermodynamic equilibrium between native and intermediate, or the rate of folding, it appears unlikely that the enzyme functions as a chaperone.
The data are consistent with a model in which the presence of glycan chains slow the inter-conversion between native and intermediate conformers, such that mAb5E3 exerts a greater effect on glycosylated material.
Similar(58)
Even the small fraction that folds to the native state at low Mg2+ levels shows sampling of conformations between native and the intermediate states.
The equilibrium reaction for IOLI involves, in addition to the native and unfolded species, a stable intermediate with significant secondary structure and stability and self-associated forms of both the native and intermediate states.
Thus, the native and intermediate states are engaged in a dynamic exchange of conformations with the equilibrium slightly favoring the native state over the intermediate.
This creates a steady exchange of conformations where native and intermediate states are constantly sampled.
An official report is a necessary step toward reconciliation between Native and non-Native Americans.
'There are large wage differences between native and mobile workers.
Motor excitability does not differ between native and non-native speakers.
Moreover, the motor excitability did not differ between native and non-native speakers.
There is also the possibility of competitive interactions between native and non-native snails [ 49].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com