Sentence examples for between mutation and polymorphism from inspiring English sources

The distinction between mutation and polymorphism on the basis of their disease-causing capacity is further complicated.

To be able to actually discriminate between mutation and selection polymorphism and divergence data would be required so that appropriate tests could be carried out (e.g., McDonald and Kreitman 1991).

The mutational spectrum does not differ between heteroplasmic mutations and polymorphisms in the same individuals, but the relative mutation rate at heteroplasmic mutations is significantly higher than that estimated for all mutable sites in the human mtDNA genome.

As it has been the case for a number of advances in the understanding of the molecular basis of disease, the in-depth analysis of the pathogenesis of PH1 has shed light into a broader field, such as the subcellular compartmentalization of enzymes or the effect of gene modifiers on phenotype and the synergy between mutations and common genetic polymorphisms.

Indeed, the significant correlation found between the number of repeat units in the SSR and ∆ al suggests a positive relationship between mutation rate, polymorphism and repeat length for these cucumber SSRs.

Therefore, subsequent analyses are sometimes needed to distinguish between pathologic mutations and polymorphisms [ 19].

In a recent thread in the ResearchGate portal [ 13], an ongoing discussion on the difference between a mutation and a polymorphism elicited a response from more than three hundred participants from various scientific backgrounds.

Our results are consistent with a recent population-based case control study that examined the relationship between 20 missense mutations and polymorphisms and breast cancer [ 14].

The estimates for degrees of Hardy-Weinberg equilibrium within each mutation and linkage disequilibrium between mutations and selection of tagging genetic polymorphisms in each of bovine UCN3 and CRHR2 genes were performed using the HAPLOVIEW program [12].

It is possible that this reduced fertility is therefore traceable to a specific interaction between the TFT mutation and a polymorphism specific to the w 1118 background (i.e. a mito-nuclear interaction involving w 1118 ).

This manuscript suffers from conceptual flaws that renders it incomprehensible and misleading: the difference between mutations, polymorphisms and substitutions is obscured to a degree that I believe in the current form makes the analysis almost meaningless.