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Are there any differences between multiple structures of the same protein?
The Rcat domains show good agreement between multiple structures of parkin (RMSD=0.9 1.3 Å) and between different proteins (parkin HHARI, RMSD=0.9 Å; parkin HOIP, RMSD=1.6 Å).
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OA can result from the dysregulation of a complex set of biomechanical and biochemical interactions between multiple structures, which can disrupt the normal homeostasis of the joint (Loeser et al., 2012; Lories, 2011).
The dynamic equilibrium between multiple structures caused by sequence and structure redundancy appear to provide entropy and stability to the overall I-motif structure.
Mair and Sherlock [ 10] described an association between injuries to multiple structures of the foot in 15 horses with high grades of OUC and another study on cadaver feet from six Finnhorses by Ruohoniemi et al. [ 11] proposed incomplete fusion lines as a potential relevant clinical finding and highlighted separate centers of ossification and medial OUC as possibly more clinically significant.
We have developed a method for superpositioning multiple structures when some of the structures have residues that other structures lack.
It does not eliminate the problem of multiple structures, however.
Theobald, D. L. & Steindel, P. A. Optimal simultaneous superpositioning of multiple structures with missing data.
You also could quickly print multiple structures simultaneously — a bunch of dice, for instance.
We constructed a multiple structure alignment of all protein kinase structures.
Students can use these programs to overlay multiple structures and measure quantitative differences between them.
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