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This relative abundance of HSFs and HSPs under cold stress could suggest a mid-point involvement in cold stress response between multiple stress pathways similar to observations made by Swindell et al. [ 26] and indicate that HSFs could have other functional features apart from heat shock responses.
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In synthesis, autophagy is connected to multiple stress pathways.
This network model structure is critical to understanding complex stresses that can simultaneously activate multiple stress pathways.
Our findings show that Hsf and Hsp family member genes represent an interaction point between multiple stress response pathways, and therefore warrant functional analysis under conditions apart from heat shock treatment.
This suggests that care must be taken with comparisons between multiple stress phenotypes.
Because DR induced the FIRE response to stress, we wondered if DR was a generally stressful condition that induced multiple stress response pathways.
Our results suggest that TaSnRK2.8 may act as a regulatory factor involved in a multiple stress response pathways.
Equally interesting was the identification of module genes participating in multiple stress responsive pathways.
Heat shock factors represent interaction points connecting multiple stress response pathways.
Many genes possibly involved in multiple biotic stress pathways were differentially regulated either constitutively or by SCN.
The genetic improvement of crop yield will need to be integrative and consider multiple stress and signalling pathways in the plant.
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