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A cohort of elegant recent studies has elicited the role of the primary cilium as a versatile mechanosensory organelle that also might coordinate cross-talk between multiple signaling pathways.
This model involves only two components, insulin and glucose, and ignores the cross talk and feedback between multiple signaling pathways.
Further studies are needed to understand the role of the complex crosstalk between multiple signaling pathways in the progression of colon cancer.
This almost certainly reflects the complex temporo-spatial interplay that occurs between multiple signaling pathways during early morphogenesis of the forebrain and facial region.
The oncogenic conversion of a primary epithelial cell to a malignant tumor involves cooperation between multiple signaling pathways, including the activation of growth-promoting signals and the inactivation of tumor-suppressor genes [ 1].
One interesting direction for further studies would be a more thorough examination of the possible crosstalk between multiple signaling pathways activated by E2 and xenoestrogens, as suggested by our previous work (Bulayeva et al. 2004, 2005; Wozniak et al. 2005).
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Vascular tissue development is regulated by complex interactions between multiple signalling pathways, and the nature of the interactions is far from clear, though progress is being made in defining the mechanisms involved [3].
Previous work suggests that midgut regeneration involves an intricate crosstalk between multiple signalling pathways.
Although interactions between SA- and JA-mediated signaling pathways have been reported to enhance the expression of plant defense-related genes, studies on interactions between JA and multiple signaling pathways (nitric oxide, hydrogen peroxide, and SA) in mediating plant secondary metabolite accumulation are rare.
Our results demonstrate that ILK plays essential roles in neural crest and outflow tract development by mediating complex crosstalk between cell matrix and multiple signaling pathways.
Functional recovery after SCI is a complex phenomenon that is not limited to a single brain structure or intracellular signaling pathways, hence requiring further study aimed at unraveling the underlying interactions between different brain structures and multiple signaling pathways.
More suggestions(14)
between apoptotic signaling pathways
between oncogenic signaling pathways
between endosomal signaling pathways
between molecular signaling pathways
between diverse signaling pathways
between multiple whisker pathways
between intracellular signaling pathways
between known signaling pathways
between sphingolipid signaling pathways
between multiple reflex pathways
between different signaling pathways
between multiple signalling pathways
between multiple stress pathways
between embryonic signaling pathways
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