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However, most likely all of these improvements will be based on the same principle, i.e. to optimize the agreement between molecular classification and external information.
21 However, the relationship between molecular classification and HBV infection remains to be elucidated.
An important association between molecular classification and LN involvement was detected (P = 0.000).
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Recently, poor concordance between molecular classification when using different algorithms has been described (i.e., they did not reliably assign the same patients to the same molecular subtypes) (Weigelt et al, 2010).
Not surprisingly, molecular classification and current prognostic signatures mainly reflect these molecular features [ 2].
PAM50 molecular classifications and BAC aCGH data were available for 282 and 234 cases respectively.
There was no significant association between the molecular classification of CNC and the relative size of the necrotic zone (P > 0.05) (Table 2).
Hoadley, K. A. et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.
They also found that approximately 42 % of sample pairs had discrepancies between histopathological classification and molecular classification using LOH patterns.
The general correspondence was observed between morphological and molecular classification.
In addition, many studies showing the relationship between immunohistochemical profiles and molecular classification of breast cancers support that IHC might play a significant role in subclassification of breast cancer patients [15], [16].
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