Sentence examples for between mitochondrial dysfunction and from inspiring English sources

These results suggest an interplay between mitochondrial dysfunction and epigenetic alterations, which may be a primary determinant of DOX-induced cardiotoxicity.

However, the molecular mechanisms underlying the cross-talk between mitochondrial dysfunction and autophagy remain to be further elucidated.

A close association between mitochondrial dysfunction and insulin resistance is well established [1] [3].

This implies that there is a synergistic interplay between mitochondrial dysfunction and amyloid burden that leads to hyperphosphorylation of tau.

A number of prior studies have found associations between mitochondrial dysfunction and AD, and animal models of AD [26], [44] [46].

Since several decades it has been shown that solid tumor cells are characterized by intense anaerobic glycolysis [32], strongly suggestive of an association between mitochondrial dysfunction and cancer.

Determining the nature of the connections between mitochondrial dysfunction, ROS and pathogenic mechanisms is a burgeoning area of great importance.

Here, we investigated cause-and-effect relationships between mitochondrial dysfunction, microtubule network disruption and accumulation of autophagosomes and autophagy substrates.

We thus propose that HCCS plays a key role in central nervous system (CNS) development by modulating a novel non-canonical start-up of cell death and provide the first experimental evidence for a mechanistic link between mitochondrial dysfunction, intrinsic apoptosis and developmental disorders.

However, the link between mitochondrial dysfunction, intrinsic apoptosis and developmental anomalies has not been demonstrated to date.

IMPACT: Our results provide the first experimental evidence for a mechanistic link between mitochondrial dysfunction, intrinsic apoptosis, and developmental disorders.