It should be also noted that because of the relatively small number of studied subjects, our study was not able to confirm unambiguously the findings already established in the literature, such as the association between skin microcirculation parameters and the subgroup parameters (e.g., duration of diabetes and HbA1c).
Analysis of microcirculation parameters (lactate, pyruvate and lactate/pyruvate ratio) was made every 6 h during the first 3 days by muscle microdialysis (CMA600, CMA microdialysis AB, Stockholm, Sweden).
The aims of the study are (1) assess the feasibility of the sublingual microcirculation monitoring in pediatric ECMO, (2) compare the microcirculation parameters under ECMO between J1 and J3.
A large study using DCE-MRI of the lumbar spine in 222 persons (healthy controls, MGUS, asymptomatic and symptomatic multiple myeloma) showed significant differences in microcirculation parameters between the different groups.
After 6 hours from resuscitation, no difference arose in the Sublingual microcirculation parameters between both groups, mean flow index after resuscitation in gelatin group (1.65 ± 0.65) which was not superior to saline group (1.74 ± 0.65).
Moreover, our results showed no significant differences between controls and group A regarding skin microcirculation parameters.
The recorded sublingual microcirculation images were analysed utilising the AVA software with a focus on the microcirculation parameters of total vessel density (TVD, mm/mm) and perfused vessel density (PVD, mm/mm).
Pathological DCE-MRI findings correlate with adverse prognostic factors and also identify patients with MGUS and asymptomatic multiple myeloma who have increased microcirculation parameters.
Increasing MAP improved sublingual microcirculation parameters without concomitant improvement in systemic tissue perfusion indicators (arterial pH, lactate, and urinary output) [ 1].
To compare microcirculation parameters with sepsis severity.
