Sentence examples for between microarray platforms and from inspiring English sources
Pathway analysis of the combined Affymetrix and Illumina datasets demonstrates a high degree of consistency between microarray platforms and between NRO and total RNA at the geneset level (Figure 3b).
Technical differences between microarray platforms and biological variability of samples can lead to differences and fluctuation in gene expression profiles.
This study also evaluated correlation in detecting differential expression between microarray platforms and TaqMan real-time PCR platform.
This is crucial for the generation of meaningful universal gene expression index based on the exchange and integration of data between microarray platforms and laboratories.
A few studies have recently been published that aimed to compare variability and consistency between microarray platforms and with different results [ 35- 37].
Both in the present study and an earlier study, we have shown that data filtering considerably improves data consistency between microarray platforms, and in particular on relative expression (log2ratios).
JFM supervised the design and development of the database and guided the gene coverage comparison between microarrays platforms and helped draft the manuscript.
The cause for discrepancies between studies, including lack of concordance between the two previously published studies, again probably represents differences between microarray platforms, statistical techniques and samples used for analysis.
Comparison and cross-validation between microarray platforms would greatly increase the understanding and value of the wealth of data generated from each microarray experiment [ 3].
This finding was consistent between different tiling microarray platforms, and between different measures of transcriptional activity, including differential binding of RNA polymerase II, and differential mRNA transcription.
Our implementation represents a straightforward, easy-to-use and open-source methodology for conversion between microarray platforms.
