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Although no significant difference between methods was seen between mean selection coefficients for passenger loci, an improvement was seen under the linked method in the assignment of selection coefficients for passenger loci at which a fixation event took place, with substantially lower mean selection coefficients being assigned.
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When implementing the classifications based on all the nodules (using the mean and median percentages of viable tumour cells, or the mean and median TRG), or the worse nodule (using the percentage of viable tumour cells or the TRG), no superiority between these methods was seen when applied to our patients.
Even larger differences between the methods are seen with respect to τ estimates.
Only a few unexplained discrepancies between the different detection methods were seen.
This allows a comparison to be made and excellent agreement between the results from the two methods is seen.
The methods are seen to perform well.
The effect modification between age and screening method was seen only for CIN 1 among women referred for colposcopy (P=0.01) and those with negative or normal findings (P=0.04), but not among subgroup of intensive screening (P=0.11).
From the figure, small disagreements between methods can be seen around the start and end points of various segments demarcated by SSTs segment view (labelled SST SEG)).
No difference in interval cancer rates between the two methods of screening was seen.
The other ten bacteria tested had greater spectrophotometric MIC95 (1.25-7.5%) values compared to visual MIC values; the biggest difference between the two methods (7.5%) was seen with S. flexneri.
An overall concordance of 76.66% between cytogradings, of 83.33% between Robinson's method and SBR, and of 66.66% between Mouriquand's method and SBR was seen.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com