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In addition, we also observed a possible association between lymph node status and the prevalence of multiple markers.
No significant interaction between lymph node status and tamoxifen was observed.
However, we did not find a significant correlation between lymph node status and patients outcome.
In 49% of patients there was a concordance between lymph node status and bone marrow status.
The relation between lymph node status and patient outcome was analyzed using Cox proportional hazards regression.
However, a significant association was observed between lymph node status and HER-2 transcript expression by qRT-PCR.
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Because of the high correlation (Pearson's R>0.80) between lymph-node status and axillary clearance, only axillary clearance was included in the model.
This suggests that the technical deficiencies of single parameter flow cytometry may have masked clinically relevant associations between lymph-node status and tumour DNA content (Beerman et al, 1990; Bergers et al, 1996; Spiethoff et al, 2000).
Spearman's coefficient of rank correlation [ 16] was used to determine the correlation between axillary lymph node status and clinical response and to evaluate the correlation between clinical response and the risk of death in disease progression.
Also shown were the associations between pathologic lymph node status and survival.
Investigation of the relationship between the lymph node status and OS was conducted using univariate and multivariate analyses.
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