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There was no significant correlation between lymph node metastasis and expression of other miRNAs.
Moreover, there is a closely associated between lymph node metastasis and VEGFR-3 expression in several lewis lung carcinoma models.
Recently a positive correlation between lymph node metastasis and a recombination of CXCR4, VEGF, and MMP-9 was reported [ 12].
A close correlation between lymph node metastasis and E-cadherin dysfunction has been reported in various types of carcinomas.
This implies a correlation between lymph node metastasis and cortactin, as suggested previously (Rothschild et al, 2006).
Expression differences between lymph node metastasis and primary CRC were tested with McNemar test, with the threshold for significance P < 0.05.
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(C) Correlation between the lymph node metastasis status and the level of miR-27b in gastric cancers (n = 19).
The relationship between cervical lymph node metastasis and US features will be one of the directions of future studies.
Patient survival analysis showed a clear positive correlation between pelvic lymph node metastasis and the overall survival in patients with cervical cancer (P<0.001, Supplementary Figure 2D).
Frequent CN deletions between axillary lymph node metastasis and BC primary tumours were revealed, including aberrations at 6q15-16, contheningenee gene PNRC1 (a putative tumour suppressor) [ 15].
Zhang XP et al reported that the number of lymph nodes detected by MDCT showed a significant difference between the lymph node metastasis group and no metastasis group in cardiac cancer [ 22].
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