But more than 200 other studies have shown links between low doses of BPA and adverse health effects, according to the Breast Cancer Fund, which is trying to ban the chemical from food and beverage containers.
Some of these researchers say that their most recent experiments--including a field study of Xenopus in South Africa, the frog's native habitat--do not support a link between low doses of atrazine and amphibian abnormalities.
These findings support a significant interaction between low doses of CLA and R-ALA for enhancement of insulin action on skeletal muscle glucose transport, possibly via reductions in muscle oxidative stress and in lipid storage.
Significant preclinical synergy was shown between low doses of NGR-TNF and doxorubicin.
In preliminary studies, we have observed a cooperativity between low doses of the MMPI and COX-2I in inducing apoptosis in cultured endothelial cells (data not shown).
Although mortality from cardiovascular diseases increased with radiation dose among atomic bomb survivors, other epidemiological data investigating the association between low doses of ionizing radiation and circulatory diseases have not provided clear evidence of such a relationship.
In fact, interactions between low-dose of X-ray (20 100 cGy) and photoreactive substrates have been reported to result in >80% enzyme inhibition in a dose-related manner similar to the effects of UV [ 2].
The lack of associations between low dose opioids and increased risks of admissions and death is consistent with the limited previous data.
Further studies, such as clinical trials with adequate power to compare the efficacy between low dose and high dose BEV, potential impact of predictive biomarkers for BEV, and comprehensive economic evaluation will strengthen the current state of knowledge on the economic value of BEV in NSCLC.
Thus we compared the interaction between a relatively low dose of lapatinib and that of a 10-fold greater dose, together with the time required to cause similar levels of killing.
