A direct correlation between lipid peroxidation and cell proliferation with increased lipid damage in highly proliferated cells has been noted [ 18].
The radical differences between Archaea and Bacteria, which are evident in the composition of their lipids and cell walls and in the utilization of different metabolic pathways, enzymes, and enzyme cofactors, are also reflected in the rRNA sequences.
Recent technological advances, such as the accurate detection and quantitation of numerous lipid species by mass spectrometry, allow the profiling of discrete changes within the lipid composition of cancer cells and will help to elucidate the intricate connections between lipid metabolism and cell function in cancer.
Negative correlations, in turn, reflected compensation or adaptation between lipids within the cell.
Our methods therefore enabled us to identify and measure dynamic correlations between lipid droplet formation and cell metabolic state, while providing insight on the spatial heterogeneity of the observed signals.
Lastly, for each species, a calibration curve would establish the relationship between fluorescence and cell lipids, as measured gravimetrically, and confirm the correct staining procedure (Table 2).
The most obvious differences in molecular and cellular functions were lipid metabolism and cell communication between the two breeds.
Other studies have shown that adipocyte-derived exosomes are involved in the control of lipid storage and cell size between adipocytes [ 10] and they have been described as mediators of angiogenesis [ 11].
Due to endpoint measurements, our experimental approach excludes the possibility to monitor dynamic bidirectional flux of lipids between HDL and cells.
Furthermore, in addition to hydrolysis of HDL-PC and -PE, the EL-mediated bridging of HDL to the cell surface [6], might further contribute to the exchange of lipids between HDL and cells.
