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Thus, overall there was no significantly linear trend between levels of lymphocyte Hsp70 and levels of exposure (p > 0.05).
However, the correlation between levels of lymphocyte Hsp70 and micronuclei frequencies was borderline (r = 0.34, p = 0.080).
Interestingly, we found significant negative correlations between levels of lymphocyte Hsp70 and the levels of various cell damage in the intermediate or high exposure subgroups.
Finally, we analyzed correlations between levels of lymphocyte and plasma Hsp70 with levels of cell damage, including DNA damage, micronuclei frequencies, and activities of MDA and LDH, and the data are shown in Table 4.
When the workers were divided into the three subgroups according to the levels of urinary 1-OHP, there was still no significant correlation between levels of lymphocyte and plasma Hsp70, genotoxic damage, and MDA concentrations in the low-exposure group; however, we found a positive correlation between plasma Hsp70 and the activity of LDH (r = 0.52, p = 0.015).
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Spearman's test was used to assess the correlation between levels of neutrophil and lymphocyte apoptosis.
However, we were unable to show significant differences between treatment groups for the change in the levels of lymphocyte tyrosine kinase activity.
No correlation was found between the % DR+ cells and the level of lymphocyte stimulation.
There was a statistically significant correlation between the levels of neutrophil and lymphocyte apoptosis in the synovial fluid samples (data not shown; Spearman r = 0.26; P = 0.004).
The levels of eosinophils, lymphocytes, basophils and monocytes showed no statistically significant differences between the three measurement periods.
Thus, correlations were made between the levels of peripheral blood human lymphocyte reconstitution and mouse hematologic parameters.
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