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Premature infants and intraoperative transfusions will not be addressed in this paper, nor will a detailed discussion of the relationship between length of storage of RBC units and outcomes, since the latter is discussed in other papers [4 7].
In this condition, no significant association between length of storage and sampling conditions was found.
In the studies by Yap et al. [ 41] and McKenny et al. [ 39], there was no association between length of storage and ICU LOS.
This implies that all studies assessing the association between length of storage and clinical outcome must take into account not only the age of the blood products, but also the total number of transfusions administered and the severity of illness.
Premature infants and intraoperative transfusions will not be addressed in this paper, nor will a detailed discussion of the relationship between length of storage of RBC units and outcomes, since the latter is discussed in other papers [ 4- 7].
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Secondary objectives included the evaluation of the relation between RBC length of storage and adverse outcome as reflected by mortality and PICU length of stay.
aStudies on the relationship between the length of storage of RBC units and outcomes of transfused cardiac patients are excluded from this table.
Caution is warranted in the interpretation of these results, which show an association between RBC length of storage and a more adverse clinical outcome in critically ill children.
Despite the limitations of our study, the observation of an independent association between longer length of storage and a greater risk of new or progressive MODS in critically ill children is a novel and important finding.
Whereas some have reported a worse clinical outcome in patients transfused with older blood [ 6, 19- 21], others did not find any association between RBC length of storage and increased morbidity or mortality [ 22- 25].
Of note, analyses of 89 TRALI cases from two tertiary care medical centres in the USA [ 7] and of 60 TRALI cases in The Netherlands [ 8] failed to demonstrate any association between the length of storage of leucoreduced PRBC and TRALI, although these analyses may have been confounded by the presence of leucocyte antibodies in a proportion of leucoreduced PRBC.
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between length of surgery
between length of hospitalization
between length of hospital
between length of life
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between length of leave
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between length of sleep
between length of ventilation
between length of exposure
between length of maternity
between length of hypoxia
between length of participation
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