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Fig. 1 Relationship between labeling efficiency and its influence factors.

Two types of positive controls were included in the experimental design: (i) synthetic small RNAs were spiked into each RNA sample before labeling to verify labeling efficiency and (ii) probes for abundant small RNAs were spotted to validate RNA quality.

In addition, both 5' and 3' sequences of 11 marmoset genes abundantly expressed in hippocampus were included as controls for assessing the overall labeling efficiency and quality of biotin-labeled target sample (Table 1).

The new chelators instantly bound to 64Cu with high labeling efficiency and maximum specific activity.

Radiolabeled nanoparticles for internal radiotherapy add another dimension of complexity, because radiolabeling often needs to be completed in short time while keeping a satisfactory labeling efficiency and radiostability.

After incubation with different concentrations of QDs with MSCs for 4 h, the MSC-labeling efficiency was very different, 15 μg/ml QDs exhibited maximal labeling efficiency, and almost all MSCs exhibited strong red fluorescence signals, which showed that almost all MSCs were successfully labeled with QDs.

Using labeling efficiency and thymic cellularity to normalize the data, we found no difference in the export rates of mature thymocytes when comparing wt and ADAM8−/− mice (Figure 4C).

The labeling efficiency and the product integrity were checked as described previously (Imbeaud et al. 2005).

LS and Lzp-PLGA-NPs formulations were effectively radiolabeled with Technetium-99m (99mTc) and optimized for maximum labeling efficiency and stability.

The integrated fluorescence intensity of each well was used to quantify the labeling efficiency and receptor cell surface expression.

With the labeling efficiency and CySC number defined, only the CySC loss/replacement rate, λ, remained to be determined.