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A washout period between interventions of at least 4 times the duration of the intervention was included after each intervention.
9 It suggested that at least 50% pain relief after 6 weeks of treatment could be a useful discriminator between interventions of greater and lesser efficacy.
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Post-hoc comparisons revealed significant differences between interventions on all dimensions of acceptability.
Finally, our study protocol might not have allowed enough time between interventions to enable establishment of a new steady state in the microcirculation.
A network of evidence represents the 'mapping' of direct comparisons between interventions (and combinations of components in interventions) as tested in included trials [ 10].
The quantitative research examined hypotheses with a focus on assessing the relation between interventions and uptake of best-practice recommendations.
To detect a clinically relevant difference between interventions (effect size of 0.4) with the primary outcome measure HADS (power of.90 and an alpha of.05) 130 completers are needed.
The procedure must have low morbidity rates, reasonably short periods of hospitalisation, a good quality of health between interventions and a high level of patient acceptance.
We have decided to use a conservative minimal important difference between intervention arms of 15 mm.
In the article that introduces the term throffer, Steiner considers the difference between interventions in the form of a threat and those in the form of an offer.
Cost-effectiveness analysis allows for comparison between interventions and makes allocation of resources explicit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com