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FVIII and FIX measurements in plasma of treated patients helps to establish the optimal interval between injections for each treated patient, and the overall therapeutic cost.
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Inject 2.0 m l aliquots of each of the concentrated extracts, prepared as directed under Control Preparation, allowing sufficient time between injections for signal peaks corresponding to the two chlorohydrin isomers to be recorded (and integrated) and for the column to be purged.
Six patients withdrew prematurely: three because of adverse events, one due to lack of efficacy and two for other reasons (missing injections during weeks 10 12 for one patient, and time interval was too long between injections for the second patient).
We then used permutation tests to compare differences between control and hormone injections (for each trait, temperature and time point) assessed from the original dataset with those from the resampled dataset.
Prescribing information (PI) for the use of biologics for psoriasis mandates different treatment intervals (ie, a different length of time between each injection) for each brand of biologic: for example, patients who use etanercept are prescribed an injection once a week, whereas patients treated with ustekinumab are prescribed one injection every 3 months during the maintenance period.
Intraocular pressure increased significantly between before and after injection for each group (Fig 1). 1 number of patients who had no akinesia, * p < 0.05 compared to group Note: SE = standard error or mean.
The summary, tumor SUVmax, SUVmean, and T/L ratio values (acquired between 35 to 40 min post-injection) for each of the study groups are shown in Table 2.
The injected dose and time lapse between injection and acquisition for each subject, as well as patient weight, can be found in Table 2.
In order to avoid complications, longer intervals between GCs injections for the weight-bearing joints have been recommended [ 52].
Whilst CD and FES spectrometers can be daisy-chained with auto-titrators, these devices consume more protein than manual titrations and offer no real speed advantage (since proteins must be fully equilibrated between denaturant injections for a true equilibrium to be established).
Each experiment had a spacing of 180 s between injections that allows for a return to baseline before the subsequent injection.
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