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The slight discrepancy between inducibility of expression of 4 × JAR RFP and B4 × JARA RFP in response to bacterial pathogens may come from the variation.
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We determined the level, tissue specificity and possible inducibility of expression for ~170 NBS-LRR-encoding and related genes.
Using stably transfected mouse embryonic fibroblast (MEF) cell lines we proved inducibility, tightness of expression and the biological functions of transgenically expressed STAT1 protein.
She demonstrated that impaired JAK2 expression leads to reduced IFN-γ based inducibility of the expression of HLA class I antigen processing machinery (APM) in melanoma cell lines.
Despite the complexity of the mechanism at play, the specific and high expression of SMPDL3B in immune cells, the inducibility of its expression and activity by immune stimuli, combined with the unequivocal phenotype observed in Smpdl3b-deficient mice, demonstrate an intimate link between a major cell surface lipid-modulating enzyme and the regulation of pro-inflammatory processes.
Accordingly, among the regulatory elements, ERE conferred the least inducibility of pporRFP expression in response to P. syringae pv.
Despite the different patter of inducibility of the expression of MIHCs, it generally depends on the presence of the main transactivator of hydrolases Xyr1 (Xylanase regulator 1).
Curiously, a hallmark of this second subgroup is a high inducibility of gene expression by BTH or its analogs [[ 18, 36] and this study].
To determine inducibility of TAM67 expression in tumours, mice were killed 7 days after the randomisation and local skin tumours were removed.
This model would also explain why Xpp1 does not influence the inducibility of xyn2 expression at early time points (compare Fig. 4a, b).
These polymorphisms may be related to altered inducibility of CYP1A2 expression by environmental chemicals and consequently influence the individual susceptibility to certain cancer.
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