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A significant correlation was found between increased expression of nuclear GLI1 and tumour stage (P < 0.001) but also between increased expression of nuclear GLI1 and the lymph node status (P = 0.027) of the analysed tumours (Table 3).
This notion is supported by studies from various laboratories that independently observed a linkage between increased expression of Notch2 and its target Hes1 and increased proliferation of renal tubular epithelial cells in the setting of various insults [ 56- 58].
We found no evidence to support a correlation between increased expression of several clock genes and timing of spawning by F. fragum.
On the contrary, one of the HapMap data sets, the GSE9372 set, revealed some degree of relation between increased expression of CDKN2A and the risk allele of the rs2891168.
Significant associations were found between increased expression of STK33 and advanced HCC staging and shorter disease-free survival of patients.
However, further investigation is required, exploring the linkage between increased expression of both Twist and ZEB via MT1-MMP.
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The concordance between the increased expression of EGFR protein and RNA was 98.1%.
A relationship between estrogens, increased expression of endometrial hormonal receptors, (HRs) and endometrial stimulation is already accepted [ 8, 9].
This supports the hypothesis that there is a correlation between the increased expression of defense-related genes and the enhanced resistance against pathogens in the ripening berry.
There also was a positive correlation between the increased expression of IL-2 and that of its three receptor chains: IL-2Rα (r = 0.88), IL-2Rβ (r = 0.97) and IL-2Rγ (r = 0.85).
Clinical outcome association analysis revealed a strong correlation between the increased expression of the genes listed above and stage progression, favorable → unfavorable disease and alive → died-of-disease (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com