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Recent data support a relationship between high serum levels of OPG and increased risk for cardiovascular disease in human.
However, a recent retrospective study revealed a strong correlation between high serum levels of caffeine and a decreased incidence of BPD in infants born ≤29 weeks GA [71].
Also, we found a relationship between high serum levels of RF and anti-CCP-2 Ab and decreased PON-1 and ARE enzymatic activities in RA patients.
The present study shows a positive association between high serum levels of 25OHD3 and moderate alcohol consumption, as opposed to high alcohol consumption and zero consumption.
While epidemiological studies have demonstrated strong associations between high serum levels of circulating oxidized low-density lipoproteins (ox-LDL) and coronary artery disease in the general population [ 65, 66], a similar association appears to hold true for patients with SLE especially in those with cardiovascular disease and antiphospholipid antibody (APA) syndrome (APS).
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There are several possible explanations for the observed associations between higher serum levels of 25-OHD and improved cancer survival.
In addition, we found a correlation between higher serum levels and the detection rate of the IGFBP-2 transcript in corresponding cells.
Moreover, a relationship between higher serum levels of the inflammatory chemokines CCL11 and CCL2 with lower lean body mass has been shown in geriatric patients [ 57].
This association and the previously reported association between higher serum levels of 25(OH D and better lung function in adults were independent of serum calcium levels, which were not associated with lung function.
Many epidemiologic and experimental studies support an association between higher serum levels of sex steroid hormones and an increased risk of postmenopausal breast cancer, especially for estrogen receptor (ER -positive brER -positive [ 1- 6].
A positive association between the use of OC and serum level of 25OHD3 was found in the present study and there was also a tendency for a positive association between MHT and high serum levels of 25OHD3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com