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Associations were identified between haplotypes defined by the three SNPs and disease progression.
rh is a measure of correlation between haplotypes defined by all SNPs and haplotypes defined by the selected htSNPs.
We investigated the association between haplotypes defined by these three SNPs and the presence of positive lymph nodes, and ER and PR status.
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To determine which combination of these potentially functional SNPs is most responsible for plasma resistin, we examined the relation between plasma resistin and haplotypes defined by SNP-420 and SNP-358 in this order (Table 4).
The rs coefficient measures LD between unmeasured SNPs and haplotypes defined by the selected tSNPs.
Because promoter region polymorphisms in the VEGF gene are in linkage disequilibrium [ 8], we examined associations between breast cancer risk and haplotypes defined by the three promoter region polymorphisms (-2578C/A, -1154G/A, and -634G/C).
Whole genome analysis revealed 15 haplotypes defined by 66 segregating sites, 19 of which are shared between two or more haplotypes, and 47 of which are found in single genomes.
The potential value of haplotypes defined by several single nucleotide polymorphisms has attracted recent interest.
Rapid progress has been made in quantifying the pattern of human LD and haplotypes defined by such common variants within and among populations.
Recombinant haplotypes defined by the haploid cell lines of other members of generation II were used to predict the other two founder haplotypes (BLUE and GREEN).
Six haplotypes, defined by six variable sites, were found.
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