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Accurate masses of features showing significant differences between groups were searched against the METLIN Metabolite Database, the Human Metabolome Database, and the Kyoto Encyclopedia of Genes and Genomes database.
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Differentially expressed transcripts between control and insulin treated groups were searched by using an empirical Bayes moderated t-test in the 'limma-package' of R and defined as having a 1.5-fold change difference and p<0.05.
Differences among groups were searched with the Kruskal-Wallis One-Way Analysis of Variance and differences between groups by Mann-Whitney's U test when the ANOVA revealed a significant difference.
These orthologous groups were searched for SNP markers and SSRs.
Studies published between 1990 to November 2015 were searched on PubMed.
Differences between groups were assessed using ANOVA.
Men in Manhattan were searched in groups, for example, while women were usually searched individually.
Differences in bacteria levels were searched for between the groups: normal patients and cancers using Mann-Whitney no parametric test.
The following databases were searched between May and June 2007 using the search term "pioglitazone metformin".
Databases were searched for studies published between 1995 and December 2011.
Significance between groups was analyzed by ANOVA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com