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Statistical significance between groups was assessed by one-way ANOVA (two-way ANOVA for body weight evolution).
Comparison between groups was assessed by Student's t-test.
Difference between groups was assessed with Student's t test or Mann-Whitney rank sum test.
The significance of differences in mortality between groups was assessed using the log-rank test.
Differences between groups was assessed using paired t tests or Wilcoxon matched - pairs signed rank tests depending on normality of data.
Where required, significance of differences between groups was assessed using Student's t test.
Statistical significance between groups was assessed using analysis of variance (ANOVA, significance level p<0.05).
For population divisions found at each k level, the significance of the Φ-statistic between groups was assessed by non-parametric randomization tests using 10 000 permutations.
Statistical significance of differences between groups was assessed with a Pearson Chi-square test or by Fisher's exact test, as appropriate.
Statistical significance between groups was assessed using analysis of variance and multiple analyses of variance (ANOVA and MANOVA, significance level p<0.05).
Reactions were performed on an iCycler iQ Multicolor Real-Time Detection System (Bio-Rad, Hercules, CA) with the following reaction conditions: 95°C for 10 min, followed by 40 cycles of 95°C for 20 sec, 60°C for 1 min, and additional incubation at 68°C for 10 min. The overall significance was assessed by 1-way ANOVA and significant difference between groups was assessed by the Student's t-test.
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