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Although day-90 mortality was not different between groups, the use of albumin in the subgroup of patients with septic shock was associated with a reduction of mortality.
However, we note that a study in which ICU propofol doses were not different between groups, the use of a BIS monitor was not associated with shorter time to extubation [ 20].
Since no changes in GL muscle activity was observed between groups, the use of shoes may be partially blocking the foot roll over process and restricting normal ankle motion, which is already altered in the diabetic population [ 38- 42].
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Schools were allocated between groups using the cluster randomization function of the WinPepi Software.
When equal variances were not assumed between groups (using the Levene test), the corrected p value was used instead.
Parametric continuous variables were compared between groups using the t test; nonparametric variables were compared using the Mann–Whitney test.
We compared the differences between groups using the paired t test.
We calculated the differences between groups using the Mann-Whitney test.
OS and RFS were calculated using the Kaplan Meier method and compared between groups using the log-rank test.
Haplotype or clade divergence was also calculated using Da distances between groups using the Kimura two-parameter model.
For the most frequently reported AEs, the incidence was compared between groups using the χ test.
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