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In our model, apart from IL-6 measurements, differences between groups for other cytokines are not clinically relevant when considering the same measurement time.
No statistically significant differences were found between groups for other comorbidities or intraoperative parameters.
Significant differences were found between groups for other parameters, and these differences are described in Table 1.
The lack of difference between groups for other sleep measures coupled with the fact that few reports included them meant there was insufficient evidence to show efficacy on these measures.
Categorical variables were compared between groups using chi-square tests or Fisher's exact test for expected counts less than 5. Logistic regression analysis was used to adjust comparisons between groups for other baseline variables.
There were no statistically significant differences between groups for other clinical outcomes, summarised in Table 4. Geometric means for times to plegia arrest (available for 307 participants in each group) were 51.3 and 51.9 s for the low and high groups, respectively (high group 1% longer, 95% CI: −6% to 9%, p = 0.79).
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There were no significant differences between groups for the other muscles.
There were no significant differences between groups for the other secondary outcomes.
(v) One-way ANOVA and Bonferroni tests were used to test for differences between study and control groups in the distribution of maternal age; chi-square tests were used to look for differences between groups for all other maternal demographics.
There were no significant differences between groups for the other secondary outcomes, except for the leisure domain of the Nottingham extended activities of daily living and the memory and thinking domain of the stroke impact scale.
However, no significant differences were observed between groups for the other variables, as is indicated by table 2. Results for mental dimensions of QoL did not reach statistical significance (shown in table 3).
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